Search on: LCK, MYOSIN 
Descriptors Found: 1
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Descriptor English:   Myosin-Light-Chain Kinase 
Descriptor Spanish:   Quinasa de Cadena Ligera de Miosina 
Descriptor Portuguese:   Quinase de Cadeia Leve de Miosina 
Synonyms English:   Myosin LCK
Myosin Regulatory Light-Chain Kinase
Kinase, Myosin
Kinase, Myosin-Light-Chain
LCK, Myosin
Myosin Light Chain Kinase
Myosin Regulatory Light Chain Kinase
Myosin Kinase  
Tree Number:   D08.811.913.696.620.682.700.125.500
D12.644.360.100.500
D12.776.476.100.500
Definition English:   An enzyme that phosphorylates myosin light chains in the presence of ATP to yield myosin-light chain phosphate and ADP, and requires calcium and CALMODULIN. The 20-kDa light chain is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors. The enzyme plays a central role in the regulation of smooth muscle contraction. 
Indexing Annotation English:   DF: MLCK
History Note English:   87 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Record Number:   19253 
Unique Identifier:   D009219 

Occurrence in VHL:
 

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